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Skin that repairs itself — from the inside out
Most skin treatments add something to your skin. Polynucleotides do something different. They tell your skin to heal itself.
Derived from highly purified salmon DNA, polynucleotides work at a cellular level — stimulating your skin's own regenerative processes to improve hydration, elasticity, and overall skin quality over time. The results are gradual, progressive, and longer lasting than most conventional skin treatments precisely because your skin is doing the work.
At Aesthetics by Emma, every polynucleotide treatment begins with a proper clinical assessment. Emma will assess your skin, discuss your concerns honestly, and recommend the right product and protocol for you.
Both polynucleotides and skin boosters are injectable treatments that improve skin quality from within, but they work in different ways and suit different patients.
Skin boosters like Profhilo use hyaluronic acid to deeply hydrate the skin and stimulate collagen and elastin production. Results are relatively quick and work well for patients whose main concern is dehydration, dullness, or loss of firmness.
Polynucleotides work at a cellular level, repairing and regenerating rather than hydrating. They take longer to show results but go deeper — making them the stronger choice for patients with more significant skin quality concerns, thinning skin, or those wanting long-term improvement rather than a maintenance treatment.
For many patients, the answer is both. Emma frequently combines polynucleotides and skin boosters as part of a broader skin treatment plan, addressing different layers of the same concern. This will be discussed at your consultation.
Read more: Polynucleotides vs Skin Boosters — What's the Difference?
Polynucleotides are fragments of purified DNA, derived from salmon and processed to the highest purity standards.
Salmon DNA has a very similar molecular structure to human DNA, which makes it highly biocompatible and well tolerated by the body.
When injected into the skin, polynucleotides act as a biological signal — prompting skin cells to repair, renew, and function more effectively.
Over a course of treatment, this leads to genuine improvements in skin quality, hydration, elasticity, and radiance that continue to develop for months after treatment.
Unlike skin boosters, which primarily hydrate, polynucleotides regenerate. They are particularly well suited to patients who want meaningful, lasting improvement in their skin health rather than a temporary top-up.
Polynucleotide treatments at Aesthetics by Emma
Plinest / Vitaran - deep skin regeneration
Plinest and Vitaran are polynucleotide injectables that work deep within the skin to promote regeneration, hydration, and repair at a cellular level. They are clinically recommended as a course of three treatments, spaced two to four weeks apart, with results continuing to develop over several months.
What they treat: dehydrated and dull skin, fine lines and early skin laxity, thinning skin, loss of elasticity, overall skin quality improvement.
A course of three is the recommended protocol for significant results. Maintenance treatments every three to six months preserve and extend those results.
Lumi-Pro Eyes PN - specialist under-eye treatment
Lumi-Pro Eyes PN is a targeted polynucleotide formulation designed specifically for the delicate skin around the eyes. It improves hydration, reduces dark circles, and smooths fine lines in an area that responds poorly to most conventional treatments.
A course of three treatments, spaced two to four weeks apart, is recommended for optimal results, with maintenance every three to six months.
Polynucleotide treatment prices
Treatment | Price | Sessions |
|---|---|---|
Vitaran/Plinest | £450 | 3 |
Vitaran/Plinest | £200 | 1 |
Lumipro Eyes PN | £250 | 3 |
Lumipro Eyes PN | £100 | 1 |
What to expect at your appointment
Your first appointment always begins with a full consultation and skin assessment. Emma will assess your skin quality, discuss your concerns, and confirm which polynucleotide treatment is right for you. There is no pressure to commit to a course on the day.
Treatment itself takes around 30 minutes.
Polynucleotides are administered by injection, typically across multiple points depending on the treatment area. Discomfort is minimal. Some temporary redness or minor swelling at injection sites is normal and settles quickly — most patients return to normal activities the same day.
Results develop gradually. Most patients begin to notice improvements after their second session, with the full benefit of the course becoming visible over the weeks and months that follow.
Frequently asked questions
Why choose Aesthetics by Emma for polynucleotides in Waterlooville?
Emma Fisher is a Registered Nurse and Independent Prescriber with over 20 years of NHS clinical experience. Every polynucleotide treatment at Aesthetics by Emma is prescribed and delivered by Emma herself — there is no remote prescriber, no separate technician, and no shortcuts.
Her approach is clinical, considered, and honest. She uses only medical-grade polynucleotide products chosen for their evidence base and safety profile, and will only recommend a course of treatment she genuinely believes will make a difference to your skin.
Aesthetics by Emma is a nurse-led aesthetics practice based in Cowplain, Waterlooville, serving patients across Portsmouth, Havant, Petersfield, Fareham and South Hampshire.